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New method of nasal vaccine delivery could lead to better vaccines for HIV and COVID-19
Promising vaccine technology has generated strong immune responses in mice and primates
Date:
August 10, 2022
Source:
University of Minnesota
Summary:
Researchers have developed a new way to effectively deliver vaccines through the nose that could lead to better protection against diseases like HIV and COVID-19.
A University of Minnesota assistant professor is part of a team that has developed a new way to effectively deliver vaccines through mucosal tissues in the nose that could lead to better protection against pathogens like human immunodeficiency virus (HIV) and SARS-CoV-2, the virus that causes COVID-19.

Hartwell is continuing to study and develop this new vaccine technology in her lab at the University of Minnesota Twin Cities and hopes to adapt it to other diseases and illnesses in the future.


The research was funded by the National Institutes of Health's National Institute of Allergy and Infectious Diseases; the National Cancer Institute; the Marble Center for Cancer Nanomedicine; the U. S. Army Research Office through the Institute for Soldier Nanotechnologies at the Massachusetts Institute of Technology; the Ragon Institute of MIT, Massachusetts General Hospital, and Harvard University; and the Bill and Melinda Gates Foundation.

In addition to Hartwell, the research team included Massachusetts Institute of Technology researchers Mariane Melo, Ashley Lemnios, Na Li, Jason Chang, Laura Maiorino, Tyson Moyer, Neil Dalvie, Sergio Rodriguez-Aponte, Kristen Rodrigues, Murillo Silva, Heikyung Suh, Josetta Adams, J. Christopher Love, and Professor Darrell Irvine; New Iberia Research Center and University of Louisiana at Lafayette researchers Peng Xiao, Crystal Carter, Jane Fontenot, Francois Villinger, and Ruth Ruprecht; Harvard Medical School researchers Jingyou Yu, Makda Gebre, Aiquan Chang, and Dan Barouch.

https://www.sciencedaily.com/releases/2022/08/220810105212.htm